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Accession IconGSE149490

Transcriptional Profiling of Lung Macrophages from Preterm Infants Identifies Disease Related Programs

Organism Icon Homo sapiens
Sample Icon 218 Downloadable Samples
Technology Badge Icon Affymetrix Human Transcriptome Array 2.0 (hta20)

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Description
To understand the molecular mechanisms of human lung macrophage development, function, and role in BPD pathogenesis, we conducted a clinical study using isolated tracheal aspirate macrophages from intubated preterm infants born before 30 wk gestation. One hundred twenty-eight patients intubated for respiratory distress syndrome and surfactant administration were consented for the study.
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