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Accession IconGSE12890

Xylose metabolism in recombinant Saccharomyces cerevisiae

Organism Icon Saccharomyces cerevisiae
Sample Icon 15 Downloadable Samples
Technology Badge Icon Affymetrix Yeast Genome S98 Array (ygs98)

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Description
In the present study transcriptome and proteome of recombinant, xylose-utilising S. cerevisiae grown in aerobic batch cultures on xylose were compared with glucose-grown cells both in glucose repressed and derepressed states. The aim was to study at genome-wide level how signalling and carbon catabolite repression differed in cells grown on either glucose or xylose. The more detailed knowledge about is xylose sensed as a fermentable carbon source, capable of catabolite repression like glucose, or is it rather recognised as a non-fermentable carbon source is important in achieving understanding for further engineering this yeast for more efficient anaerobic fermentation of xylose.
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