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Accession IconGSE119756

Analysis of gene expression in brains of DO1 treated and untreated 5xFAD and control mice using a microarray technology

Organism Icon Mus musculus
Sample Icon 23 Downloadable Samples
Technology Badge IconIllumina MouseWG-6 v2.0 R2 expression beadchip

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Description
Transcripts of 4 groups of treated and untreated mice (TG+DO1, TG, WT+DO1 and WT) were systematically investigated. Results revealed a clear separation of data obtained from AD and non-AD brains (Figure 6A), confirming previous observations (Landel et al., 2014). Furthermore, we observed that the compound DO1 alters the transcriptional profiles in brains of 5xFAD and wild-type control mice.
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