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Accession IconE-MEXP-3452

Transcription profiling by array of pig whole blood from individuals with high and low serum interferon-alpha production which were stimulated with virus mimic dsRNA (Poly I:C)

Organism Icon Sus scrofa
Sample Icon 12 Downloadable Samples
Technology Badge Icon Affymetrix Porcine Genome Array (porcine)

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Description
The interferon (IFN) is a major effector of the innate immunity which mediates an adaptive immune response against broad spectrum pathogens. The aim of this work has been to investigate the differences of the virus mimic dsRNA (Poly I:C)-inducted in vivo transcriptomic alteration between pigs with high (HIGH) and low (LOW) serum interferon-alpha production. The pigs with extreme yield of induced interferon-alpha from a F2 resource population were selected for whole blood gene expression analysis using the porcine Affymetrix microarray
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